Rekombinantes human-LBP (huLBP)

Grunwald, U., X. Fan, R. S. Jack, G. Workalemahu, A. Kallis, F. Stelter, C. Schütt, 1996

Monocytes can phagozytose Gram-negative bacteria by a CD14 - dependent mechanism. J. Immunol. 157: 41

 

Bochkov, V.N. Kadl,A. Huber, J. Gruber F. et al Protective role of phospholipid oxidation products in endotoxin-induced tissue damage, Letters to Nature 2002, 419: 77-81

 

He,Y.-W. Li,H. Zhang,J. et al The extracellular matrix protein mindin is apattern-recognition molecule for microbial pathogens, Nature Immunology 2003,5:88-97

 

Heinzelmann, M., Bossart, H., Heparin binds to lipopolysaccharide (LPS)-Binding protein, facilitates the transfer of LPS to CD14, and enhances LPS-induced activation of peripheral blood monocytes, J. immunol., 2005, 174: 2280-2287

 

Hermann, C. Spreitzer, I., Schröder, N.W.J. et al Cytokine induktion by purified lipoteichoic acids from various bacterial species-Role of LBP,sCD14,CD14 and failure to induce IL-12 and subsequent IFN – release, Eur. J. Immunology 2002,32(2): 541-551

 

Jack, R.S. et al.(1995): Both membrane bound and soluble forms of CD14 bind to gram negative bacteria. Eur. J. Immunol. 25, 1436